hi Maggie,i am on 25 inj mtx,the tablets took too long to get into my system been inj same dose now 4+years and yes the headaches/side effects are horrendous,i get very hot so I think I am wired up wrong,my feet feel odd for the 2 days and I get a real burst of energy about a hour after I jnj then I have to sleep maybe about 2/3 hours later for about a hour or so or I just feel so bad I cant function right at all,i have worked it out now so I know when to get home and lie down,i make sure I don't have must do's on that day, i take 6 folic now as I was so tired and had the hair loss thing,my nurse at the time advised me and I have been ok since but it still floors me for 2/3 days I just work through it but do have a full rest day every 3 days if I can,my family and close friends are good as they know if I say not today I mean not today and they back off,its just getting what works for you,take a look at what you eat too as I found too much of a certain something can contribute to the down sides, MUST use 50+ sun factor when on mtx,even if out and in all day when strong sun is out,i got caught out just didn't think and I got a skin reaction it was awful now I buy nivea kids it goes on green and dries invisible,have fun,dorothy
